Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.F442S

c.1325T>C

Surrounding Variants

1 paper

NM_198291.3

p.F442Y

c.1325T>A

1 paper

NM_198291.3

p.T443S

c.1327A>T

1 paper

NM_198291.3

p.T443S

c.1328C>G

1 paper

NM_198291.3

p.R441H

c.1322G>A

1 paper

NM_198291.3

p.R441C

c.1321C>T

1 paper

NM_198291.3

p.G440D

c.1319G>A

1 paper

NM_198291.3

p.I444N

c.1331T>A

1 paper

NM_198291.3

p.G440S

c.1318G>A

1 paper

NM_198291.3

p.K445T

c.1334A>C

1 paper

NM_198291.3

p.Y439C

c.1316A>G

1 paper

NM_198291.3

p.S446A

c.1336T>G

1 paper

NM_198291.3

p.S446W

c.1337C>G