Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.G452E

c.1355G>A

Surrounding Variants

1 paper

NM_198291.3

p.I453V

c.1357A>G

1 paper

NM_198291.3

p.S450Y

c.1349C>A

1 paper

NM_198291.3

p.L454Q

c.1361T>A

1 paper

NM_198291.3

p.W449C

c.1347G>T

2 papers

NM_198291.3

p.V448M

c.1342G>A

1 paper

NM_198291.3

p.E457K

c.1369G>A

8 papers

NM_198291.3

p.E457A

c.1370A>C

1 paper

NM_198291.3

p.D447N

c.1339G>A

2 papers

NM_198291.3

p.E457D

c.1371G>C

2 papers

NM_198291.3

p.E457D

c.1371G>T

1 paper

NM_198291.3

p.L458V

c.1372C>G

1 paper

NM_198291.3

p.S446W

c.1337C>G