Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.R463R

c.1389G>T

Surrounding Variants

1 paper

NM_198291.3

p.R463Q

c.1388G>A

1 paper

NM_198291.3

p.R463G

c.1387C>G

1 paper

NM_198291.3

p.P465S

c.1393C>T

1 paper

NM_198291.3

p.P465R

c.1394C>G

1 paper

NM_198291.3

p.G462R

c.1384G>A

1 paper

NM_198291.3

p.G462R

c.1384G>C

1 paper

NM_198291.3

p.T460K

c.1379C>A

1 paper

NM_198291.3

p.P467L

c.1400C>T

1 paper

NM_198291.3

p.T459N

c.1376C>A

1 paper

NM_198291.3

p.T459S

c.1376C>G

1 paper

NM_198291.3

p.G468A

c.1403G>C

2 papers

NM_198291.3

p.G468V

c.1403G>T