Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.E489Q

c.1465G>C

Surrounding Variants

1 paper

NM_198291.3

p.P488L

c.1463C>T

1 paper

NM_198291.3

p.C490Y

c.1469G>A

4 papers

NM_198291.3

p.P487L

c.1460C>T

1 paper

NM_198291.3

p.P487T

c.1459C>A

1 paper

NM_198291.3

p.C486Y

c.1457G>A

2 papers

NM_198291.3

p.E492K

c.1474G>A

1 paper

NM_198291.3

p.E492V

c.1475A>T

1 paper

NM_198291.3

p.P485L

c.1454C>T

1 paper

NM_198291.3

p.P485S

c.1453C>T

1 paper

NM_198291.3

p.S493T

c.1477T>A

1 paper

NM_198291.3

p.S493P

c.1477T>C

2 papers

NM_198291.3

p.S493Y

c.1478C>A