Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.R503Q

c.1508G>A

Surrounding Variants

2 papers

NM_198291.3

p.R503W

c.1507C>T

2 papers

NM_198291.3

p.E505K

c.1513G>A

1 paper

NM_198291.3

p.E505G

c.1514A>G

1 paper

NM_198291.3

p.E505D

c.1515G>C

1 paper

NM_198291.3

p.E505D

c.1515G>T

1 paper

NM_198291.3

p.P506S

c.1516C>T

2 papers

NM_198291.3

p.E507K

c.1519G>A

1 paper

NM_198291.3

p.E507*

c.1519G>T

1 paper

NM_198291.3

p.C499Y

c.1496G>A

1 paper

NM_198291.3

p.E507D

c.1521G>C

1 paper

NM_198291.3

p.E507D

c.1521G>T

2 papers

NM_198291.3

p.C499R

c.1495T>C