Varaico: Literature-Extracted Genetic Variants

SSRP1

109 papers

RefSeq Summary

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to ef...

Pfam Domains

POB3_Naa 5–99UCSCPOB3-like N-terminal PH domain

SSrecogaa 106–170UCSCStructure-specific recognition protein (SSRP1)

PH1_SSRP1-likeaa 197–326UCSCSSRP1 PH domain

Rttp106-like_middleaa 339–427UCSCHistone chaperone Rttp106-like, middle domain

HMG_boxaa 547–615UCSCHMG (high mobility group) box

SSRP1_Caa 657–705UCSCFACT complex subunit SSRP1, C-terminal domain

Gene Aliases

HGNC Name

structure specific recognition protein 1

HGNC Alias Symbol

FACT80

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003146.3

p.K599R

c.1796A>G

Surrounding Variants

1 paper

NM_003146.3

p.K599Q

c.1795A>C

2 papers

NM_003146.3

p.D606H

c.1816G>C

1 paper

NM_003146.3

p.G616R

c.1846G>C

1 paper

NM_003146.3

p.G616R

c.1846G>A

1 paper

NM_003146.3

p.K593K

c.1779A>G

1 paper

NM_003146.3

p.W585G

c.1753T>G

1 paper

NM_003146.3

p.I584V

c.1750A>G

1 paper

NM_003146.3

p.T575M

c.1724C>T

1 paper

NM_003146.3

p.T575A

c.1723A>G

1 paper

NM_003146.3

p.S573N

c.1718G>A

1 paper

NM_003146.3

p.H569Y

c.1705C>T

1 paper

NM_003146.3

p.K564M

c.1691A>T