ST3 beta-galactoside alpha-2,3-sialyltransferase 3

SIAT6

MRT12

sialyltransferase 6 (N-acetyllactosaminide alpha 2,3-sialyltransferase)

mental retardation, non-syndromic, autosomal recessive, 12

ST3Gal III

N-acetyllactosaminide alpha-2,3-sialyltransferase

CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase

Beta-galactoside alpha-2,3-sialyltransferase 3

Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase

ST3N

Sialyltransferase 6

Alpha 2,3-ST 3

ST3GalIII

Glycosyltransferase family 29 (sialyltransferase)

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017].

Varaico: Literature-Extracted Genetic Variants

ST3GAL3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbols