Varaico: Literature-Extracted Genetic Variants

STAT1

1,286 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and the...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 143–309UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 321–458UCSCSTAT protein, DNA binding domain

STAT_linkeraa 480–558UCSCSignal transducer and activator of transcription, linker domain

SH2aa 573–651UCSCSH2 domain

STAT1_TAZ2bindaa 715–739UCSCSTAT1 TAZ2 binding domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 1

HGNC Alias Symbols

STAT91; ISGF-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007315.4

p.N297del1

c.889_890delGTT

Surrounding Variants

8 papers

NM_007315.4

p.K298N

c.894A>T

8 papers

NM_007315.4

p.K298N

c.894A>C

2 papers

NM_007315.4

p.K298R

c.893A>G

1 paper

NM_007315.4

p.N297delFs

c.890delT

1 paper

NM_007315.4

p.V300L

c.898G>T

1 paper

NM_007315.4

p.V300L

c.898G>C

1 paper

NM_007315.4

p.N297S

c.890A>G

1 paper

NM_007315.4

p.K296fs

c.886_887fs

1 paper

NM_007315.4

p.K296R

c.887A>G

1 paper

NM_007315.4

p.L301S

c.902T>C

1 paper

NM_007315.4

p.T295K

c.884C>A

5 papers

NM_007315.4

p.L301del1

c.901_902delTAA