Varaico: Literature-Extracted Genetic Variants

STAT2

360 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and the...

Pfam Domains

STAT_intaa 2–123UCSCSTAT protein, protein interaction domain

STAT_alphaaa 146–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–456UCSCSTAT protein, DNA binding domain

STAT_linkeraa 479–557UCSCSignal transducer and activator of transcription, linker domain

SH2aa 577–648UCSCSH2 domain

STAT2_Caa 783–838UCSCSignal transducer and activator of transcription 2 C terminal

Gene Aliases

HGNC Name

signal transducer and activator of transcription 2

HGNC Alias Symbol

STAT113

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005419.4

p.C809S

c.2426G>C

Surrounding Variants

2 papers

NM_005419.4

p.C809S

c.2425T>A

1 paper

NM_005419.4

p.R807G

c.2419A>G

1 paper

NM_005419.4

p.G819A

c.2456G>C

1 paper

NM_005419.4

p.D820_P821delins

c.2460_2461delinsCT

11 papers

NM_005419.4

p.G825C

c.2473G>T

1 paper

NM_005419.4

p.A824_G825delins

c.2472_2473delinsCT

2 papers

NM_005419.4

p.G825D

c.2474G>A

11 papers

NM_005419.4

p.Q826H

c.2478G>T

NM_198332.2

p.Q822H

c.2466G>T

10 papers

NM_005419.4

p.Q826H

c.2478G>C

NM_198332.2

p.Q822H

c.2466G>C

1 paper

NM_005419.4

p.N818_N827del10

c.2452_2480del30

1 paper

NM_005419.4

p.V829M

c.2485G>A

1 paper

NM_005419.4

p.R836H

c.2507G>A