Varaico: Literature-Extracted Genetic Variants

STAT2

360 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and the...

Pfam Domains

STAT_intaa 2–123UCSCSTAT protein, protein interaction domain

STAT_alphaaa 146–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–456UCSCSTAT protein, DNA binding domain

STAT_linkeraa 479–557UCSCSignal transducer and activator of transcription, linker domain

SH2aa 577–648UCSCSH2 domain

STAT2_Caa 783–838UCSCSignal transducer and activator of transcription 2 C terminal

Gene Aliases

HGNC Name

signal transducer and activator of transcription 2

HGNC Alias Symbol

STAT113

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005419.4

p.Q326*

c.976C>T

Surrounding Variants

1 paper

NM_005419.4

p.P328S

c.982C>T

6 papers

NM_005419.4

p.R330*

c.988C>T

3 papers

NM_005419.4

p.R330Q

c.989G>A

1 paper

NM_005419.4

p.E319G

c.956A>G

1 paper

NM_005419.4

p.E319K

c.955G>A

1 paper

NM_005419.4

p.R314G

c.940A>G

1 paper

NM_005419.4

p.V342I

c.1024G>A

1 paper

NM_198332.2

p.T340T

c.1020A>G

1 paper

NM_005419.4

p.L311V

c.931C>G

1 paper

NM_005419.4

p.L308L

c.922C>T

1 paper

NM_005419.4

p.A302T

c.904G>A

1 paper

NM_005419.4

p.P292L

c.875C>T