Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

1–12 of 293 variants

8 papers

NM_003151.4

p.T446I

c.1337C>T

7 papers

NM_003151.4

p.H623Y

c.1867C>T

6 papers

NM_003151.4

p.E128V

c.383A>T

4 papers

NM_003151.4

p.R240Q

c.719G>A

4 papers

NM_003151.4

p.L269I

c.805C>A

4 papers

NM_003151.4

p.S371Splc

c.1113-4C>T

4 papers

NM_003151.4

p.A635V

c.1904C>T

4 papers

NM_003151.4

p.A650D

c.1949C>A

3 papers

NM_003151.4

p.E50G

c.149A>G

3 papers

NM_003151.4

p.Q91_G92Splc

c.274-23582A>C

3 papers

NM_003151.4

p.T446T

c.1338C>A

3 papers

NM_003151.4

p.E651V

c.1952A>T