Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_003151.4

p.A635V

c.1904C>T

Surrounding Variants

1 paper

NM_003151.4

p.F638L

c.1912T>C

1 paper

NM_003151.4

p.R632R

c.1896G>A

1 paper

NM_003151.4

p.R632Q

c.1895G>A

1 paper

NM_003151.4

p.F638L

c.1914C>G

1 paper

NM_003151.4

p.F638L

c.1914C>A

1 paper

NM_003151.4

p.A639T

c.1915G>A

2 papers

NM_003151.4

p.E626G

c.1877A>G

7 papers

NM_003151.4

p.H623Y

c.1867C>T

4 papers

NM_003151.4

p.A650D

c.1949C>A

3 papers

NM_003151.4

p.E651V

c.1952A>T

1 paper

NM_003151.4

p.I653M

c.1959T>G

1 paper

NM_003151.4

p.N656S

c.1967A>G