Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003151.4

p.Y470C

c.1409A>G

Surrounding Variants

1 paper

NM_003151.4

p.V472M

c.1414G>A

1 paper

NM_003151.4

p.S473L

c.1418C>T

1 paper

NM_003151.4

p.A463_W464del0

c.1387_1392del6

1 paper

NM_003151.4

p.D476N

c.1426G>A

1 paper

NM_003151.4

p.N475delFs

c.1425delG

1 paper

NM_003151.4

p.N462_A463delFs

c.1386_1387delCA

3 papers

NM_003151.4

p.T446T

c.1338C>A

8 papers

NM_003151.4

p.T446I

c.1337C>T

1 paper

NM_003151.4

p.E445_T446Splc

c.1336-50T>C

1 paper

NM_003151.4

p.E445_T446Splc

c.1335+5G>A

1 paper

NM_003151.4

p.C436_L437delFs

c.1308_1309delGG

1 paper

NM_003151.4

p.I435insFs

c.1303dupA