Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003151.4

p.S371Splc

c.1112+18T>C

Surrounding Variants

4 papers

NM_003151.4

p.S371Splc

c.1113-4C>T

1 paper

NM_003151.4

p.I387T

c.1160T>C

1 paper

NM_003151.4

p.E388*

c.1162G>T

1 paper

NM_003151.4

p.E388D

c.1164A>T

1 paper

NM_003151.4

p.E388D

c.1164A>C

1 paper

NM_003151.4

p.N392D

c.1174A>G

1 paper

NM_003151.4

p.S391delFs

c.1172delG

2 papers

NM_003151.4

p.G393A

c.1178G>C

1 paper

NM_003151.4

p.S396S

c.1188A>G

1 paper

NM_003151.4

p.S396S

c.1188A>C

1 paper

NM_003151.4

p.K365Splc

c.1094+10C>A

1 paper

NM_003151.4

p.K365Splc

c.1094+1G>T