Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003151.4

p.K365Splc

c.1094+1G>T

Surrounding Variants

1 paper

NM_003151.4

p.K365Splc

c.1094+10C>A

1 paper

NM_003151.4

p.S362*

c.1085C>A

1 paper

NM_003151.4

p.A361T

c.1081G>A

1 paper

NM_003151.4

p.Y355_Q356del1

c.1064_1066delGAT

1 paper

NM_003151.4

p.Y355N

c.1063T>A

1 paper

NM_003151.4

p.L347R

c.1040T>G

1 paper

NM_003151.4

p.S371Splc

c.1112+18T>C

4 papers

NM_003151.4

p.S371Splc

c.1113-4C>T

1 paper

NM_003151.4

p.I387T

c.1160T>C

1 paper

NM_003151.4

p.E388*

c.1162G>T

1 paper

NM_003151.4

p.E388D

c.1164A>T

1 paper

NM_003151.4

p.E388D

c.1164A>C