Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_003151.4

p.L269I

c.805C>A

Surrounding Variants

1 paper

NM_003151.4

p.R273insFs

c.817dupA

1 paper

NM_003151.4

p.R273_R274delFs

c.819_822del4

1 paper

NM_003151.4

p.E280*

c.838G>T

1 paper

NM_003151.4

p.K285del1

c.853_854delTTT

1 paper

NM_003151.4

p.M286I

c.858G>T

1 paper

NM_003151.4

p.M286I

c.858G>C

1 paper

NM_003151.4

p.M286I

c.858G>A

1 paper

NM_003151.4

p.Y288N

c.862T>A

1 paper

NM_003151.4

p.Y288*

c.864T>G

1 paper

NM_003151.4

p.Y288*

c.864T>A

1 paper

NM_003151.4

p.E289G

c.866A>G

1 paper

NM_003151.4

p.P292T

c.874C>A