Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003151.4

p.S134F

c.401C>T

Surrounding Variants

1 paper

NM_003151.4

p.K129_S133del5

c.385_398del15

1 paper

NM_003151.4

p.E138Q

c.412G>C

1 paper

NM_003151.4

p.S130S

c.390C>A

1 paper

NM_003151.4

p.K129insFs

c.387dupA

1 paper

NM_003151.4

p.Q140*

c.418C>T

6 papers

NM_003151.4

p.E128V

c.383A>T

1 paper

NM_003151.4

p.P126A

c.376C>G

1 paper

NM_003151.4

p.V143G

c.428T>G

1 paper

NM_003151.4

p.G125W

c.373G>T

1 paper

NM_003151.4

p.V147L

c.439G>T

1 paper

NM_003151.4

p.V147L

c.439G>C

1 paper

NM_003151.4

p.A149T

c.445G>A