Varaico: Literature-Extracted Genetic Variants

STAT4

325 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 144–308UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 320–454UCSCSTAT protein, DNA binding domain

STAT_linkeraa 476–554UCSCSignal transducer and activator of transcription, linker domain

SH2aa 569–644UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003151.4

p.L61_I62insFs

c.183_184insCC

Surrounding Variants

1 paper

NM_003151.4

p.I62delFs

c.185delA

1 paper

NM_003151.4

p.Q63R

c.188A>G

1 paper

NM_003151.4

p.Q58R

c.173A>G

1 paper

NM_003151.4

p.D65G

c.194A>G

1 paper

NM_003151.4

p.E66*

c.196G>T

1 paper

NM_003151.4

p.E66G

c.197A>G

1 paper

NM_003151.4

p.E66A

c.197A>C

1 paper

NM_003151.4

p.R70L

c.209G>T

1 paper

NM_003151.4

p.M52I

c.156G>T

1 paper

NM_003151.4

p.M52I

c.156G>C

1 paper

NM_003151.4

p.M52I

c.156G>A

1 paper

NM_003151.4

p.T51S

c.152C>G