Varaico: Literature-Extracted Genetic Variants

STAT5A

650 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–124UCSCSTAT protein, protein interaction domain

STAT_alphaaa 145–324UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 336–469UCSCSTAT protein, DNA binding domain

STAT_linkeraa 491–574UCSCSignal transducer and activator of transcription, linker domain

SH2aa 593–670UCSCSH2 domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 5A

HGNC Previous Symbol

STAT5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_001288718.2

p.A630P

c.1888G>C

Surrounding Variants

1 paper

NM_001288718.2

p.A630T

c.1888G>A

1 paper

NM_001288718.2

p.W631R

c.1891T>A

1 paper

NM_001288718.2

p.W631R

c.1891T>C

1 paper

NM_001288718.2

p.T628_I629insFs

c.1884_1885insG

4 papers

NM_001288718.2

p.T628S

c.1883C>G

4 papers

NM_001288718.2

p.T628S

c.1882A>T

1 paper

NM_001288718.2

p.I627M

c.1881C>G

2 papers

NM_001288718.2

p.P636S

c.1906C>T

1 paper

NM_001288718.2

p.S622ins1

c.1865_1866insGAA

1 paper

NM_001288718.2

p.F619_G625ins2

c.1855_1875dup21

1 paper

NM_001288718.2

p.R618H

c.1853G>A

1 paper

NM_001288718.2

p.R618G

c.1852C>G