Varaico: Literature-Extracted Genetic Variants

STAT6

483 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–114UCSCSTAT protein, protein interaction domain

STAT_alphaaa 148–262UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 277–413UCSCSTAT protein, DNA binding domain

STAT_linkeraa 435–518UCSCSignal transducer and activator of transcription, linker domain

SH2aa 537–616UCSCSH2 domain

STAT6_Caa 655–847UCSCSTAT6 C-terminal

Gene Aliases

HGNC Name

signal transducer and activator of transcription 6

HGNC Alias Symbols

D12S1644; IL-4-STAT

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003153.5

p.M435L

c.1303A>C

Surrounding Variants

1 paper

NM_003153.5

p.M435L

c.1303A>T

1 paper

NM_003153.5

p.E434K

c.1300G>A

1 paper

NM_003153.5

p.M435_D436Splc

c.1305+6G>A

1 paper

NM_003153.5

p.A431A

c.1293C>T

3 papers

NM_003153.5

p.N430S

c.1289A>G

2 papers

NM_003153.5

p.N430T

c.1289A>C

2 papers

NM_003153.5

p.A424_L427del4

c.1270_1280del12

1 paper

NM_003153.5

p.I426V

c.1276A>G

1 paper

NM_003153.5

p.K423E

c.1267A>G

9 papers

NM_003153.5

p.N421K

c.1263T>G

9 papers

NM_003153.5

p.N421K

c.1263T>A

2 papers

NM_003153.5

p.N421S

c.1262A>G