Varaico: Literature-Extracted Genetic Variants

STAT6

483 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–114UCSCSTAT protein, protein interaction domain

STAT_alphaaa 148–262UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 277–413UCSCSTAT protein, DNA binding domain

STAT_linkeraa 435–518UCSCSignal transducer and activator of transcription, linker domain

SH2aa 537–616UCSCSH2 domain

STAT6_Caa 655–847UCSCSTAT6 C-terminal

Gene Aliases

HGNC Name

signal transducer and activator of transcription 6

HGNC Alias Symbols

D12S1644; IL-4-STAT

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003153.5

p.L403R

c.1208T>G

Surrounding Variants

1 paper

NM_003153.5

p.Q404K

c.1210C>A

1 paper

NM_003153.5

p.L403delFs

c.1209delG

1 paper

NM_003153.5

p.P400R

c.1199C>G

1 paper

NM_003153.5

p.K398R

c.1193A>G

1 paper

NM_003153.5

p.G397_K398insFs

c.1191_1192insG

1 paper

NM_003153.5

p.A390S

c.1168G>T

5 papers

NM_003153.5

p.E382Q

c.1144G>C

1 paper

NM_003153.5

p.E382K

c.1144G>A

1 paper

NM_003153.5

p.E377D

c.1131G>T

1 paper

NM_003153.5

p.E377D

c.1131G>C

3 papers

NM_003153.5

p.E377Q

c.1129G>C

14 papers

NM_003153.5

p.E377K

c.1129G>A