Varaico: Literature-Extracted Genetic Variants

STEAP3

65 papers

RefSeq Summary

This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream res...

Pfam Domains

F420_oxidoredaa 30–117UCSCNADP oxidoreductase coenzyme F420-dependent

Ferric_reductaa 259–405UCSCFerric reductase like transmembrane component

Gene Aliases

HGNC Name

STEAP3 metalloreductase

HGNC Alias Symbols

TSAP6; dudlin-2; STMP3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 51 variants

4 papers

NM_182915.3

p.T495M

c.1484C>T

2 papers

NM_182915.3

p.A184T

c.550G>A

2 papers

NM_182915.3

p.R336C

c.1006C>T

1 paper

NM_182915.3

p.A8Splc

c.22+14G>T

1 paper

NM_182915.3

p.E14_L19delFs

c.42_57del16

1 paper

NM_182915.3

p.D28N

c.82G>A

1 paper

NM_182915.3

p.G45R

c.133G>C

1 paper

NM_182915.3

p.R69C

c.205C>T

1 paper

NM_182915.3

p.P79P

c.237C>T

1 paper

NM_182915.3

p.V91G

c.272T>G

1 paper

NM_018234.3

p.C100*

c.300C>A

1 paper

NM_182915.3

p.I120V

c.358A>G