Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.Q273L

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_198282.4
p.Q273L
c.818A>T
Surrounding Variants
2 papers
NM_198282.4
p.Y274D
c.820T>G
1 paper
NM_198282.4
p.Y274C
c.821A>G
1 paper
NM_198282.4
p.S272A
c.814T>G
1 paper
NM_198282.4
p.M271V
c.811A>G
1 paper
NM_198282.4
p.Q276K
c.826C>A
2 papers
NM_198282.4
p.Q276P
c.827A>C
4 papers
NM_198282.4
p.F269S
c.806T>C
1 paper
NM_198282.4
p.F269Y
c.806T>A
1 paper
NM_198282.4
p.L268S
c.803T>C
1 paper
NM_198282.4
p.G278D
c.833G>A
19 papers
NM_198282.4
p.F279L
c.835T>C
2 papers
NM_198282.4
p.T267I
c.800C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."