Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.E260V

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_198282.4
p.E260V
c.779A>T
Surrounding Variants
1 paper
NM_198282.4
p.E260G
c.779A>G
4 papers
NM_198282.4
p.E260A
c.779A>C
1 paper
NM_198282.4
p.E260Q
c.778G>C
1 paper
NM_198282.4
p.Y261F
c.782A>T
1 paper
NM_198282.4
p.T263S
c.787A>T
3 papers
NM_198282.4
p.T263A
c.787A>G
1 paper
NM_198282.4
p.T263S
c.788C>G
1 paper
NM_198282.4
p.P264A
c.790C>G
1 paper
NM_198282.4
p.P264fs
c.790_791fs
1 paper
NM_198282.4
p.L265fs
c.793_794fs
1 paper
NM_198282.4
p.Q266*
c.796C>T
2 papers
NM_198282.4
p.A254V
c.761C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."