Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.R253W

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_198282.4
p.R253W
c.757C>T
Surrounding Variants
1 paper
NM_198282.4
p.R253Q
c.758G>A
2 papers
NM_198282.4
p.G251E
c.752G>A
1 paper
NM_198282.4
p.E246K
c.736G>A
1 paper
NM_198282.4
p.Y245F
c.734A>T
1 paper
NM_198282.4
p.I244V
c.730A>G
1 paper
NM_198282.4
p.Y240F
c.719A>T
1 paper
NM_198282.4
p.Y240C
c.719A>G
1 paper
NM_198282.4
p.R238W
c.712C>T
1 paper
NM_198282.4
p.D237N
c.709G>A
5 papers
NM_198282.4
p.K236R
c.707A>G
1 paper
NM_198282.4
p.I235L
c.703A>C
1 paper
NM_198282.4
p.A233S
c.697G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."