Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.I200N

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_198282.4
p.I200N
c.599T>A
Surrounding Variants
1 paper
NM_198282.4
p.L201R
c.602T>G
1 paper
NM_198282.4
p.Y199F
c.596A>T
1 paper
NM_198282.4
p.Y199C
c.596A>G
2 papers
NM_198282.4
p.L202F
c.604C>T
1 paper
NM_198282.4
p.P203S
c.607C>T
3 papers
NM_198282.4
p.R197Q
c.590G>A
1 paper
NM_198282.4
p.R197W
c.589C>T
1 paper
NM_198282.4
p.Q196R
c.587A>G
1 paper
NM_198282.4
p.D205Y
c.613G>T
1 paper
NM_198282.4
p.D205H
c.613G>C
1 paper
NM_198282.4
p.D205N
c.613G>A
5 papers
NM_198282.4
p.C206G
c.616T>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."