Varaico: Literature-Extracted Genetic Variants

Gene:STK10
Variant:p.D647G

STK10

99 papers

RefSeq Summary

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like...

Pfam Domains

Pkinaseaa 36–294UCSCProtein kinase domain
PKKaa 587–725UCSCPolo kinase kinase
PKKaa 755–895UCSCPolo kinase kinase

Gene Aliases

HGNC Name

serine/threonine kinase 10

HGNC Alias Symbols

LOK; PRO2729

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005990.4
p.D647G
c.1940A>G
Surrounding Variants
1 paper
NM_005990.4
p.R648W
c.1942C>T
1 paper
NM_005990.4
p.R643P
c.1928G>C
1 paper
NM_005990.4
p.R643H
c.1928G>A
2 papers
NM_005990.4
p.L657P
c.1970T>C
1 paper
NM_005990.4
p.R636L
c.1907G>T
1 paper
NM_005990.4
p.R634H
c.1901G>A
2 papers
NM_005990.4
p.M627L
c.1879A>T
2 papers
NM_005990.4
p.M627L
c.1879A>C
2 papers
NM_005990.4
p.R618H
c.1853G>A
1 paper
NM_005990.4
p.R618C
c.1852C>T
1 paper
NM_005990.4
p.Q590H
c.1770G>T
1 paper
NM_005990.4
p.Q590H
c.1770G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."