Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.R42_A43insFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000455.5
p.R42_A43insFs
c.126_127insC
Surrounding Variants
1 paper
NM_000455.5
p.R42R
c.126G>C
1 paper
NM_000455.5
p.A43P
c.127G>C
1 paper
NM_000455.5
p.A43fs
c.127_128fs
1 paper
NM_000455.5
p.R42insFs
c.125_126insT
7 papers
NM_000455.5
p.R42L
c.125G>T
3 papers
NM_000455.5
p.A43S
c.127G>T
1 paper
NM_000455.5
p.A43delFs
c.129delC
1 paper
NM_000455.5
p.A43fs
c.127_128fs
2 papers
NM_000455.5
p.A43_L50del8
c.127_149del24
1 paper
NM_000455.5
p.R42insFs
c.125dupG
2 papers
NM_000455.5
p.R42fs
c.124_125fs
1 paper
NM_000455.5
p.R42W
c.124C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."