Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.Y60fs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000455.5
p.Y60fs
c.178_179fs
Surrounding Variants
1 paper
NM_000455.5
p.Y60N
c.178T>A
11 papers
NM_000455.5
p.Y60insFs
c.179dupA
2 papers
NM_000455.5
p.Y60insFs
c.179_180insGA
12 papers
NM_000455.5
p.Y60fs
c.178_179fs
2 papers
NM_000455.5
p.Y60delFs
c.179_180delAC
1 paper
NM_000455.5
p.Y60F
c.179A>T
15 papers
NM_000455.5
p.Y60delFs
c.180delC
1 paper
NM_000455.5
p.Y60_G61del1
c.180_182delCGG
57 papers
NM_000455.5
p.Y60*
c.180C>A
1 paper
NM_000455.5
p.Y60insFs
c.178_179insT
58 papers
NM_000455.5
p.Y60*
c.180C>G
1 paper
NM_000455.5
p.S59C
c.176C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."