Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.G61delFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.G61delFs
c.181_182delGG
Surrounding Variants
57 papers
NM_000455.5
p.Y60*
c.180C>A
58 papers
NM_000455.5
p.Y60*
c.180C>G
1 paper
NM_000455.5
p.Y60Y
c.180C>T
1 paper
NM_000455.5
p.Y60_G61delins
c.180_181delinsAA
5 papers
NM_000455.5
p.G61delFs
c.182delG
1 paper
NM_000455.5
p.Y60F
c.179A>T
15 papers
NM_000455.5
p.Y60delFs
c.180delC
1 paper
NM_000455.5
p.Y60_G61del1
c.180_182delCGG
1 paper
NM_000455.5
p.G61S
c.181G>A
1 paper
NM_000455.5
p.G61R
c.181G>C
2 papers
NM_000455.5
p.G61fs
c.181_182fs
1 paper
NM_000455.5
p.G61C
c.181G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."