Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.V63E

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.V63E
c.188T>A
Surrounding Variants
2 papers
NM_000455.5
p.V63A
c.188T>C
1 paper
NM_000455.5
p.V63G
c.188T>G
3 papers
NM_000455.5
p.V63M
c.187G>A
1 paper
NM_000455.5
p.V63L
c.187G>C
1 paper
NM_000455.5
p.K64insFs
c.190dupA
1 paper
NM_000455.5
p.V63fs
c.187_188fs
1 paper
NM_000455.5
p.K64E
c.190A>G
4 papers
NM_000455.5
p.K62N
c.186G>C
4 papers
NM_000455.5
p.K62N
c.186G>T
1 paper
NM_000455.5
p.K64insFs
c.192dupG
1 paper
NM_000455.5
p.K64R
c.191A>G
1 paper
NM_000455.5
p.K62M
c.185A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."