Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.A76fs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.A76fs
c.226_227fs
Surrounding Variants
2 papers
NM_000455.5
p.A76fs
c.226_227fs
1 paper
NM_000455.5
p.A76delFs
c.227delC
1 paper
NM_000455.5
p.A76V
c.227C>T
1 paper
NM_000455.5
p.A76_V77delFs
c.228_229delCG
2 papers
NM_000455.5
p.V77del1
c.229_230delGTC
1 paper
NM_000455.5
p.A76A
c.228C>A
1 paper
NM_000455.5
p.A76A
c.228C>T
1 paper
NM_000455.5
p.R75M
c.224G>T
1 paper
NM_000455.5
p.A76delFs
c.226delG
1 paper
NM_000455.5
p.R75_L80del0
c.224_238del15
2 papers
NM_000455.5
p.V77I
c.229G>A
1 paper
NM_000455.5
p.V77L
c.229G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."