Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.K84R

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.K84R
c.251A>G
Surrounding Variants
1 paper
NM_000455.5
p.K84T
c.251A>C
1 paper
NM_000455.5
p.K84delFs
c.252delG
1 paper
NM_000455.5
p.L85_R87del3
c.253_260del9
1 paper
NM_000455.5
p.K84fs
c.250_251fs
45 papers
NM_000455.5
p.K84*
c.250A>T
1 paper
NM_000455.5
p.K84K
c.252G>A
1 paper
NM_000455.5
p.K83K
c.249G>A
1 paper
NM_000455.5
p.K84delFs
c.250delA
1 paper
NM_000455.5
p.L85M
c.253T>A
1 paper
NM_000455.5
p.L85_R87delFs
c.254_260del7
1 paper
NM_000455.5
p.K83delFs
c.249delG
1 paper
NM_000455.5
p.L85*
c.254T>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."