Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.Q159*

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
18 papers
NM_000455.5
p.Q159*
c.475C>T
Surrounding Variants
1 paper
NM_000455.5
p.Q159delFs
c.476delA
2 papers
NM_000455.5
p.Q159fs
c.475_476fs
2 papers
NM_000455.5
p.C158*
c.474T>A
1 paper
NM_000455.5
p.C158W
c.474T>G
1 paper
NM_000455.5
p.Q159delFs
c.475_476delCA
1 paper
NM_000455.5
p.C158Y
c.473G>A
1 paper
NM_000455.5
p.L160insFs
c.478dupC
2 papers
NM_000455.5
p.C158F
c.473G>T
1 paper
NM_000455.5
p.C158delFs
c.474delT
1 paper
NM_000455.5
p.L160_I161insC
c.478_482ins3
1 paper
NM_000455.5
p.L160_I161insC*
c.478_482ins6
1 paper
NM_000455.5
p.C158fs
c.472_473fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."