Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.I161_G163delFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.I161_G163delFs
c.482_489del8
Surrounding Variants
1 paper
NM_000455.5
p.I161fs
c.481_482fs
1 paper
NM_000455.5
p.I161insFs
c.482_483ins10
3 papers
NM_000455.5
p.I161F
c.481A>T
1 paper
NM_000455.5
p.L160_I161delins
c.480_481delinsTT
1 paper
NM_000455.5
p.I161_G163del3
c.481_488del9
1 paper
NM_000455.5
p.I161_L167delFs
c.483_499del17
1 paper
NM_000455.5
p.L160Q
c.479T>A
1 paper
NM_000455.5
p.L160P
c.479T>C
1 paper
NM_000455.5
p.I161I
c.483T>C
1 paper
NM_000455.5
p.L160R
c.479T>G
1 paper
NM_000455.5
p.I161M
c.483T>G
1 paper
NM_000455.5
p.G163insFs
c.488_489ins4
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."