Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.S193fs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.S193fs
c.577_578fs
Surrounding Variants
1 paper
NM_000455.5
p.S193A
c.577T>G
1 paper
NM_000455.5
p.S193fs
c.577_578fs
1 paper
NM_000455.5
p.S193delFs
c.579delC
3 papers
NM_000455.5
p.S193Y
c.578C>A
1 paper
NM_000455.5
p.S193_D194delFs
c.577_581del5
1 paper
NM_000455.5
p.D194delFs
c.580_581delGA
1 paper
NM_000455.5
p.I192N
c.575T>A
2 papers
NM_000455.5
p.I192insFs
c.575_576insA
1 paper
NM_000455.5
p.I192fs
c.574_575fs
1 paper
NM_000455.5
p.S193delFs
c.577_578delTC
65 papers
NM_000455.5
p.D194N
c.580G>A
11 papers
NM_000455.5
p.D194H
c.580G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."