Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.G215_S216Fs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.G215_S216Fs
c.644_648delinsTCTFs
Surrounding Variants
7 papers
NM_000455.5
p.G215D
c.644G>A
1 paper
NM_000455.5
p.G215V
c.644G>T
1 paper
NM_000455.5
p.S216_Q220delFs
c.646_658del13
1 paper
NM_000455.5
p.S216insFs
c.646dupT
3 papers
NM_000455.5
p.G215S
c.643G>A
1 paper
NM_000455.5
p.G215C
c.643G>T
3 papers
NM_000455.5
p.P217insFs
c.650_651insC
1 paper
NM_000455.5
p.S216fs
c.646_647fs
2 papers
NM_000455.5
p.P217delFs
c.650delC
1 paper
NM_000455.5
p.S216fs
c.646_647fs
9 papers
NM_000455.5
p.Q214_G215del1
c.642_644delGGG
4 papers
NM_000455.5
p.S216Y
c.647C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."