Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.F219delFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.F219delFs
c.657delC
Surrounding Variants
1 paper
NM_000455.5
p.Q220delFs
c.658_659delCA
2 papers
NM_000455.5
p.F219fs
c.655_656fs
44 papers
NM_000455.5
p.Q220*
c.658C>T
1 paper
NM_000455.5
p.Q220P
c.659A>C
1 paper
NM_000455.5
p.Q220R
c.659A>G
1 paper
NM_000455.5
p.Q220L
c.659A>T
1 paper
NM_000455.5
p.Q220delFs
c.660delG
2 papers
NM_000455.5
p.A218delFs
c.654delT
1 paper
NM_000455.5
p.F219delFs
c.655_656delTT
2 papers
NM_000455.5
p.A218fs
c.652_653fs
1 paper
NM_000455.5
p.A218S
c.652G>T
2 papers
NM_000455.5
p.A218fs
c.652_653fs
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."