Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.Q220P

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.Q220P
c.659A>C
Surrounding Variants
1 paper
NM_000455.5
p.Q220R
c.659A>G
1 paper
NM_000455.5
p.Q220L
c.659A>T
1 paper
NM_000455.5
p.Q220delFs
c.660delG
44 papers
NM_000455.5
p.Q220*
c.658C>T
1 paper
NM_000455.5
p.P221_P222insA
c.661_665ins3
1 paper
NM_000455.5
p.Q220delFs
c.658_659delCA
1 paper
NM_000455.5
p.P221delFs
c.662_663delCG
1 paper
NM_000455.5
p.P221fs
c.661_662fs
1 paper
NM_000455.5
p.P221_G227Fs
c.661_680delinsGCGCFs
3 papers
NM_000455.5
p.P221R
c.662C>G
11 papers
NM_000455.5
p.P221L
c.662C>T
1 paper
NM_000455.5
p.F219delFs
c.657delC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."