Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.I224insFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.I224insFs
c.672dupT
Surrounding Variants
1 paper
NM_000455.5
p.I224F
c.670A>T
1 paper
NM_000455.5
p.I224_I238del15
c.670_713del45
4 papers
NM_000455.5
p.E223V
c.668A>T
6 papers
NM_000455.5
p.E223K
c.667G>A
9 papers
NM_000455.5
p.E223fs
c.667_668fs
1 paper
NM_000455.5
p.A225fs
c.673_674fs
21 papers
NM_000455.5
p.E223*
c.667G>T
1 paper
NM_000455.5
p.E223delFs
c.668delA
1 paper
NM_000455.5
p.A225delFs
c.675delC
9 papers
NM_000455.5
p.P222_E223insFs
c.666_667insGG
1 paper
NM_000455.5
p.N226_G227insFs
c.676_679dup4
1 paper
NM_000455.5
p.P222insFs
c.665_666insT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."