Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.L228_D229del2

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.L228_D229del2
c.682_686del6
Surrounding Variants
1 paper
NM_000455.5
p.G227V
c.680G>T
1 paper
NM_000455.5
p.L228_S232delFs
c.683_696del14
1 paper
NM_000455.5
p.G227S
c.679G>A
3 papers
NM_000455.5
p.L228fs
c.682_683fs
1 paper
NM_000455.5
p.L228delFs
c.683delT
1 paper
NM_000455.5
p.N226S
c.677A>G
1 paper
NM_000455.5
p.L228delFs
c.684delG
1 paper
NM_000455.5
p.N226fs
c.676_677fs
1 paper
NM_000455.5
p.N226fs
c.676_677fs
1 paper
NM_000455.5
p.N226_G227insFs
c.676_679dup4
1 paper
NM_000455.5
p.D229delFs
c.686_687delAC
1 paper
NM_000455.5
p.D229fs
c.685_686fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."