Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.E256*

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
19 papers
NM_000455.5
p.E256*
c.766G>T
Surrounding Variants
7 papers
NM_000455.5
p.E256K
c.766G>A
1 paper
NM_000455.5
p.E256A
c.767A>C
1 paper
NM_000455.5
p.E256V
c.767A>T
2 papers
NM_000455.5
p.F255L
c.765C>A
2 papers
NM_000455.5
p.F255L
c.765C>G
6 papers
NM_000455.5
p.D258delFs
c.772delG
2 papers
NM_000455.5
p.F255S
c.764T>C
2 papers
NM_000455.5
p.G257R
c.769G>A
2 papers
NM_000455.5
p.G257R
c.769G>C
4 papers
NM_000455.5
p.G257fs
c.769_770fs
1 paper
NM_000455.5
p.G257W
c.769G>T
2 papers
NM_000455.5
p.F255L
c.763T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."