Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.D258fs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000455.5
p.D258fs
c.772_773fs
Surrounding Variants
1 paper
NM_000455.5
p.D258N
c.772G>A
3 papers
NM_000455.5
p.D258fs
c.772_773fs
1 paper
NM_000455.5
p.D258delins
c.772_774delinsACG
1 paper
NM_000455.5
p.N259del1
c.775_776delAAC
1 paper
NM_000455.5
p.D258G
c.773A>G
1 paper
NM_000455.5
p.D258V
c.773A>T
1 paper
NM_000455.5
p.G257E
c.770G>A
1 paper
NM_000455.5
p.G257V
c.770G>T
1 paper
NM_000455.5
p.G257_N259delFs
c.771_775del5
1 paper
NM_000455.5
p.I260_Y261del2
c.778_782del6
1 paper
NM_000455.5
p.I260_Y272del13
c.778_815del39
2 papers
NM_000455.5
p.G257R
c.769G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."