Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.Y261delFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000455.5
p.Y261delFs
c.781delT
Surrounding Variants
10 papers
NM_000455.5
p.I260fs
c.778_779fs
1 paper
NM_000455.5
p.Y261S
c.782A>C
1 paper
NM_000455.5
p.Y261C
c.782A>G
1 paper
NM_000455.5
p.Y261F
c.782A>T
10 papers
NM_000455.5
p.I260delFs
c.779delT
3 papers
NM_000455.5
p.Y261*
c.783C>A
1 paper
NM_000455.5
p.N259K
c.777C>A
4 papers
NM_000455.5
p.Y261*
c.783C>G
1 paper
NM_000455.5
p.K262_L263del2
c.784_788del6
1 paper
NM_000455.5
p.N259T
c.776A>C
1 paper
NM_000455.5
p.K262*
c.784A>T
2 papers
NM_000455.5
p.K262fs
c.784_785fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."