Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.G268insFs

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.G268insFs
c.803_804ins26
Surrounding Variants
2 papers
NM_000455.5
p.G268E
c.803G>A
1 paper
NM_000455.5
p.G268A
c.803G>C
6 papers
NM_000455.5
p.G268R
c.802G>A
6 papers
NM_000455.5
p.G268R
c.802G>C
1 paper
NM_000455.5
p.G268W
c.802G>T
1 paper
NM_000455.5
p.G268fs
c.802_803fs
2 papers
NM_000455.5
p.K269fs
c.805_806fs
1 paper
NM_000455.5
p.K269*
c.805A>T
1 paper
NM_000455.5
p.K269fs
c.805_806fs
1 paper
NM_000455.5
p.G268_K269insFs
c.804_805insG
1 paper
NM_000455.5
p.I267I
c.801C>T
1 paper
NM_000455.5
p.G268delFs
c.804delG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."