Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.P275S

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000455.5
p.P275S
c.823C>T
Surrounding Variants
1 paper
NM_000455.5
p.P275fs
c.823_824fs
1 paper
NM_000455.5
p.P275A
c.823C>G
1 paper
NM_000455.5
p.P275fs
c.823_824fs
1 paper
NM_000455.5
p.P275_D277delFs
c.825_831del7
1 paper
NM_000455.5
p.P275Q
c.824C>A
5 papers
NM_000455.5
p.P275L
c.824C>T
4 papers
NM_000455.5
p.G276delFs
c.826delG
1 paper
NM_000455.5
p.I274Fs
c.821delinsACFs
1 paper
NM_000455.5
p.I274T
c.821T>C
2 papers
NM_000455.5
p.P275insFs
c.824dupC
1 paper
NM_000455.5
p.I274delFs
c.822delC
2 papers
NM_000455.5
p.G276S
c.826G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."