Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.P281_L282del1

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.P281_L282del1
c.842_844delCGC
Surrounding Variants
3 papers
NM_000455.5
p.P281T
c.841C>A
1 paper
NM_000455.5
p.P280H
c.839C>A
40 papers
NM_000455.5
p.P281fs
c.841_842fs
1 paper
NM_000455.5
p.P281A
c.841C>G
5 papers
NM_000455.5
p.P280L
c.839C>T
1 paper
NM_000455.5
p.P281delFs
c.842_843delCG
26 papers
NM_000455.5
p.P281fs
c.841_842fs
1 paper
NM_000455.5
p.P281_L282insFs
c.843_844insG
1 paper
NM_000455.5
p.L282_D284insFs
c.844_850dup7
1 paper
NM_000455.5
p.P281insFs
c.842_843insT
3 papers
NM_000455.5
p.P280A
c.838C>G
2 papers
NM_000455.5
p.P281R
c.842C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."