Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.D284H

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.D284H
c.850G>C
Surrounding Variants
1 paper
NM_000455.5
p.D284fs
c.850_851fs
1 paper
NM_000455.5
p.D284_L285insG
c.850_854ins3
1 paper
NM_000455.5
p.D284A
c.851A>C
1 paper
NM_000455.5
p.D284delFs
c.850delG
1 paper
NM_000455.5
p.D284_K287delFs
c.850_860del11
1 paper
NM_000455.5
p.D284E
c.852C>A
1 paper
NM_000455.5
p.D284E
c.852C>G
3 papers
NM_000455.5
p.S283F
c.848C>T
1 paper
NM_000455.5
p.S283fs
c.847_848fs
2 papers
NM_000455.5
p.S283_D284delFs
c.848_852del5
6 papers
NM_000455.5
p.L285Q
c.854T>A
1 paper
NM_000455.5
p.L285P
c.854T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."