Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.P321L

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.P321L
c.962C>T
Surrounding Variants
1 paper
NM_000455.5
p.P321P
c.963C>A
1 paper
NM_000455.5
p.P321fs
c.961_962fs
2 papers
NM_000455.5
p.P321S
c.961C>T
1 paper
NM_000455.5
p.P321fs
c.961_962fs
3 papers
NM_000455.5
p.I322fs
c.964_965fs
1 paper
NM_000455.5
p.I322L
c.964A>C
1 paper
NM_000455.5
p.V320V
c.960G>A
1 paper
NM_000455.5
p.P321insFs
c.961dupC
1 paper
NM_000455.5
p.V320_P321insFs
c.960_961insT
4 papers
NM_000455.5
p.P321delFs
c.961delC
4 papers
NM_000455.5
p.P321delFs
c.962_963delCC
1 paper
NM_000455.5
p.I322T
c.965T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."