Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.E357D

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.E357D
c.1071G>T
Surrounding Variants
1 paper
NM_000455.5
p.E357D
c.1071G>C
1 paper
NM_000455.5
p.D358N
c.1072G>A
1 paper
NM_000455.5
p.D358fs
c.1072_1073fs
5 papers
NM_000455.5
p.E357K
c.1069G>A
1 paper
NM_000455.5
p.E357fs
c.1069_1070fs
2 papers
NM_000455.5
p.D359_D365del7
c.1075_1094del21
1 paper
NM_000455.5
p.D359insFs
c.1076dupA
1 paper
NM_000455.5
p.I356T
c.1067T>C
1 paper
NM_000455.5
p.D359G
c.1076A>G
1 paper
NM_000455.5
p.D359_F366Fs
c.1076_1096delinsTGTAAGGFs
1 paper
NM_000455.5
p.D355E
c.1065C>A
1 paper
NM_000455.5
p.D355E
c.1065C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."